Back to Search
Start Over
Relation Classification for Bleeding Events From Electronic Health Records Using Deep Learning Systems: An Empirical Study
- Source :
- JMIR Medical Informatics, Vol 9, Iss 7, p e27527 (2021), JMIR Medical Informatics
- Publication Year :
- 2021
- Publisher :
- JMIR Publications, 2021.
-
Abstract
- Background Accurate detection of bleeding events from electronic health records (EHRs) is crucial for identifying and characterizing different common and serious medical problems. To extract such information from EHRs, it is essential to identify the relations between bleeding events and related clinical entities (eg, bleeding anatomic sites and lab tests). With the advent of natural language processing (NLP) and deep learning (DL)-based techniques, many studies have focused on their applicability for various clinical applications. However, no prior work has utilized DL to extract relations between bleeding events and relevant entities. Objective In this study, we aimed to evaluate multiple DL systems on a novel EHR data set for bleeding event–related relation classification. Methods We first expert annotated a new data set of 1046 deidentified EHR notes for bleeding events and their attributes. On this data set, we evaluated three state-of-the-art DL architectures for the bleeding event relation classification task, namely, convolutional neural network (CNN), attention-guided graph convolutional network (AGGCN), and Bidirectional Encoder Representations from Transformers (BERT). We used three BERT-based models, namely, BERT pretrained on biomedical data (BioBERT), BioBERT pretrained on clinical text (Bio+Clinical BERT), and BioBERT pretrained on EHR notes (EhrBERT). Results Our experiments showed that the BERT-based models significantly outperformed the CNN and AGGCN models. Specifically, BioBERT achieved a macro F1 score of 0.842, outperforming both the AGGCN (macro F1 score, 0.828) and CNN models (macro F1 score, 0.763) by 1.4% (P Conclusions In this comprehensive study, we explored and compared different DL systems to classify relations between bleeding events and other medical concepts. On our corpus, BERT-based models outperformed other DL models for identifying the relations of bleeding-related entities. In addition to pretrained contextualized word representation, BERT-based models benefited from the use of target entity representation over traditional sequence representation
- Subjects :
- Computer science
Computer applications to medicine. Medical informatics
R858-859.7
Health Informatics
computer.software_genre
Convolutional neural network
relation classification
03 medical and health sciences
0302 clinical medicine
Health Information Management
030212 general & internal medicine
Macro
Representation (mathematics)
030304 developmental biology
Original Paper
0303 health sciences
Event (computing)
business.industry
Deep learning
bleeding
GCN
Data set
electronic health records
Graph (abstract data type)
Artificial intelligence
F1 score
business
computer
CNN
Natural language processing
BERT
Subjects
Details
- Language :
- English
- ISSN :
- 22919694
- Volume :
- 9
- Issue :
- 7
- Database :
- OpenAIRE
- Journal :
- JMIR Medical Informatics
- Accession number :
- edsair.doi.dedup.....d39b1afb03a2845c59294e685e0e2df3