Back to Search
Start Over
Risk factors of postoperative pulmonary complications in patients with asthma and COPD
- Source :
- BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018), BMC Pulmonary Medicine
- Publication Year :
- 2018
- Publisher :
- BMC, 2018.
-
Abstract
- Background Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to evaluate perioperative management using new inhalant drugs in patients with obstructive pulmonary diseases. Methods April 2014 through March 2015, 346 adult patients with pulmonary diseases (257 asthma, 89 chronic obstructive pulmonary disease (COPD)) underwent non-pulmonary surgery except cataract surgery in our university hospital. To analyze the risk factors for PPC, we retrospectively evaluated physiological backgrounds, surgical factors and perioperative specific treatment for asthma and COPD. Results Finally, 29 patients with pulmonary diseases (22 asthma, 7 COPD) had PPC. In patients with asthma, smoking index (≥ 20 pack-years), peripheral blood eosinophil count (≥ 200/mm3) and severity (Global INitiative for Asthma(GINA) STEP ≥ 3) were significantly associated with PPC in the multivariate logistic regression analysis [odds ratio (95% confidence interval) = 5.4(1.4–20.8), 0.31 (0.11–0.84) and 3.2 (1.04–9.9), respectively]. In patients with COPD, age, introducing treatment for COPD, upper abdominal surgery and operation time (≥ 5 h) were significantly associated with PPC [1.18 (1.00–1.40), 0.09 (0.01–0.81), 21.2 (1.3–349) and 9.5 (1.2–77.4), respectively]. Conclusions History of smoking or severe asthma is a risk factor of PPC in patients with asthma, and age, upper abdominal surgery, or long operation time is a risk factor of PPC in patients with COPD. Adequate inhaled corticosteroids treatment in patients with eosinophilic asthma and introducing treatment for COPD in patients with COPD could reduce PPCs.
- Subjects :
- Adult
Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Neutrophils
medicine.medical_treatment
Operative Time
Severity of Illness Index
Leukocyte Count
Pulmonary Disease, Chronic Obstructive
Young Adult
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Internal medicine
Abdomen
medicine
Humans
COPD
030212 general & internal medicine
Risk factor
Aged
Retrospective Studies
Asthma
Aged, 80 and over
lcsh:RC705-779
business.industry
Smoking
Age Factors
Perioperative
Odds ratio
lcsh:Diseases of the respiratory system
Middle Aged
Eosinophil
Cataract surgery
medicine.disease
Confidence interval
respiratory tract diseases
Eosinophils
medicine.anatomical_structure
030228 respiratory system
Risk factors
Female
business
Postoperative pulmonary complication
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 14712466
- Volume :
- 18
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Pulmonary Medicine
- Accession number :
- edsair.doi.dedup.....d37d94975b8c609a6cb496ceb4f5d11d