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Weak rTMS-induced electric fields produce neural entrainment in humans
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020), Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Research, 2020.
-
Abstract
- Repetitive transcranial magnetic stimulation (rTMS) is a potent tool for modulating endogenous oscillations in humans. The current standard method for rTMS defines the stimulation intensity based on the evoked liminal response in the visual or motor system (e.g., resting motor threshold). The key limitation of the current approach is that the magnitude of the resulting electric field remains elusive. A better characterization of the electric field strength induced by a given rTMS protocol is necessary in order to improve the understanding of the neural mechanisms of rTMS. In this study we used a novel approach, in which individualized prospective computational modeling of the induced electric field guided the choice of stimulation intensity. We consistently found that rhythmic rTMS protocols increased neural synchronization in the posterior alpha frequency band when measured simultaneously with scalp electroencephalography. We observed this effect already at electric field strengths of roughly half the lowest conventional field strength, which is 80% of the resting motor threshold. We conclude that rTMS can induce immediate electrophysiological effects at much weaker electric field strengths than previously thought. Open-Access-Publikationsfonds 2020 peerReviewed
- Subjects :
- Adult
Male
Electroencephalography - EEG
VDP::Social science: 200::Psychology: 260
lcsh:Medicine
Motor Activity
behavioral disciplines and activities
Article
Young Adult
bepress|Life Sciences|Neuroscience and Neurobiology
Electricity
Humans
lcsh:Science
bepress|Life Sciences|Neuroscience and Neurobiology|Systems Neuroscience
lcsh:R
Brain
PsyArXiv|Neuroscience|Systems Neuroscience
Transcranial Magnetic Stimulation
Alpha Rhythm
PsyArXiv|Neuroscience
Electroencephalography – EEG
Neuroscience
Transcranial magnetic stimulation
VDP::Samfunnsvitenskap: 200::Psykologi: 260
Female
lcsh:Q
Artifacts
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020), Scientific Reports
- Accession number :
- edsair.doi.dedup.....d2e914efd1d511585896974b5100d6e6