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Modality transition on renal replacement therapy and quality of life of patients: a 10-year follow-up cohort study
- Source :
- Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. 28(6)
- Publication Year :
- 2019
-
Abstract
- Despite advance in renal replacement therapy (RRT), patients with chronic end-stage renal disease (ESRD) face various limitations, and renal transplantation (Tx) is the treatment that impacts most on quality of life (QoL). This study aimed to assess changes in QoL in a cohort of ESRD dialysis patients. Sociodemographic, clinical, nutritional, lifestyle, and QoL data were collected from 712 patients at baseline (time 1) and after 10 years of follow-up (time 2) for patients surviving. The QoL was assessed through the 36-Item Short Form Health Survey (SF-36) and the multiple linear regression model was used to analyze the factors associated with change in QoL. A total of 205 survivors were assessed and distributed into three groups according to current RRT (Dialysis–Dialysis, Dialysis–Tx, and Dialysis–Tx–Dialysis). At time 1, only age was significantly different among groups; at time 2, transplant patients sustained greater social participation, job retention, and improvement in SF-36 scores. The factors associated with change in QoL were more time on dialysis interfering negatively on physical functioning (p = 0.002), role-physical limitations (p = 0.002), general health (p = 0.007), social functioning (p = 0.02), role-emotional (p = 0.003), and physical components ( p = 0.002); non-participation in social groups at times 1 and 2 reducing vitality (p = 0.02) scores; and having work at time 2, increasing vitality (p = 0.02) and mental health (p = 0.02) scores. QoL was shown to be dynamic throughout the years of RRT, transplantation being the treatment with more benefits to the ESRD. More time on dialysis and limited social and occupational routine were associated with a reduction in QoL.
- Subjects :
- Adult
Male
medicine.medical_specialty
medicine.medical_treatment
Emotions
Disease
End stage renal disease
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Quality of life
Renal Dialysis
Internal medicine
Medicine
Humans
Renal replacement therapy
Survivors
Dialysis
business.industry
030503 health policy & services
Public Health, Environmental and Occupational Health
Middle Aged
Social Participation
Kidney Transplantation
Transplantation
Renal Replacement Therapy
Mental Health
030220 oncology & carcinogenesis
Cohort
Quality of Life
Kidney Failure, Chronic
Female
0305 other medical science
business
Cohort study
Follow-Up Studies
Subjects
Details
- ISSN :
- 15732649
- Volume :
- 28
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
- Accession number :
- edsair.doi.dedup.....d2d40f04355c58d1bb67632c781c1530