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Brown Seaweeds for the Management of Metabolic Syndrome and Associated Diseases
- Source :
- Molecules, Molecules, Vol 25, Iss 4182, p 4182 (2020)
- Publication Year :
- 2020
- Publisher :
- MDPI AG, 2020.
-
Abstract
- Metabolic syndrome is characterized by the coexistence of different metabolic disorders which increase the risk of developing type 2 diabetes mellitus and cardiovascular diseases. Therefore, metabolic syndrome leads to a reduction in patients’ quality of life as well as to an increase in morbidity and mortality. In the last few decades, it has been demonstrated that seaweeds exert multiple beneficial effects by virtue of their micro- and macronutrient content, which could help in the management of cardiovascular and metabolic diseases. This review aims to provide an updated overview on the potential of brown seaweeds for the prevention and management of metabolic syndrome and its associated diseases, based on the most recent evidence obtained from in vitro and in vivo preclinical and clinical studies. Owing to their great potential for health benefits, brown seaweeds are successfully used in some nutraceuticals and functional foods for treating metabolic syndrome comorbidities. However, some issues still need to be tackled and deepened to improve the knowledge of their ADME/Tox profile in humans, in particular by finding validated indexes of their absorption and obtaining reliable information on their efficacy and long-term safety.
- Subjects :
- Ascophyllum nodosum
Cardiovascular diseases
Diabetes
Fucus vesiculosus
Hypertension
Laminaria japonica
Metabolic syndrome
NAFLD
Obesity
Seaweeds
Undaria pinnatifida
030309 nutrition & dietetics
Pharmaceutical Science
Review
Health benefits
Bioinformatics
Undaria
Analytical Chemistry
Functional Food
Drug Discovery
Ascophyllum
0303 health sciences
Chemistry (miscellaneous)
Molecular Medicine
Laminaria
lcsh:QD241-441
03 medical and health sciences
Quality of life (healthcare)
Nutraceutical
lcsh:Organic chemistry
Diabetes mellitus
medicine
Animals
Humans
In patient
Physical and Theoretical Chemistry
030304 developmental biology
business.industry
Plant Extracts
Organic Chemistry
Type 2 Diabetes Mellitus
Polyphenols
medicine.disease
Seaweed
Diabetes Mellitus, Type 2
Dietary Supplements
Fucus
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Molecules, Molecules, Vol 25, Iss 4182, p 4182 (2020)
- Accession number :
- edsair.doi.dedup.....d2ccabbf7644351bb47d15d07976f6a2