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Insight into hepatocellular carcinoma biology with gadoxetate disodium-enhanced MRI
- Source :
- Kagen, Alexander; Fowler, Kathryn; & Sirlin, Claude B. (2014). Insight into hepatocellular carcinoma biology with gadoxetate disodium-enhanced MRI.. Hepatic oncology, 1(1), 95-105. doi: 10.2217/hep.13.11. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/8qg6g78v
- Publication Year :
- 2018
-
Abstract
- SUMMARY The current algorithm for the imaging diagnosis of hepatocellular carcinoma accurately detects large, progressed tumors displaying the classical imaging features of arterial hyperenhancement with ‘washout’ and/or ‘capsule’ appearance. Liver MRI with the relatively newer hepatobiliary agent, gadoxetate disodium, provides information on hepatocellular function in addition to vascularity, facilitates detection of small progressed tumors, as well as early/vaguely nodular tumors, and shows promise for characterizing hepatocellular carcinoma biology. Prediction of tumor grade, presence of biliary and stem cell markers, microvascular invasion, future hypervascularization and post-treatment recurrence have all been studied with gadoxetate disodium-enhanced MRI with encouraging results. Incorporation of gadoxetate disodium-enhanced MRI into standard diagnostic and management algorithms will likely unfold in the future.
Details
- ISSN :
- 20450931
- Volume :
- 1
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Hepatic oncology
- Accession number :
- edsair.doi.dedup.....d2c739a86b34a8cf6fd43ccc98159b6b