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A simple sensitive ratiometric fluorescent probe for the detection of mercury ions in living cells and zebrafish
- Source :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 249:119279
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- Mercury, as a highly toxic heavy metal, can cause very serious harm to human health and even death in severe cases. Therefore, we synthesized a novel ratiometric fluorescent probe for detecting mercury ions, with mercaptoethanol as the recognition receptor. Probe CMER could determine mercury ions in 0–1.6 μM and the detection limit is 7.6 nM. Moreover, CMER manifested a fast response for Hg2+ (within 5 s) and simultaneously observed that the color changed from light yellow to orange by naked eye. In addition to these preeminent spectral properties, the probe also had satisfactory bioimaging results in RAW 264.7 macrophage cells and zebrafish.
- Subjects :
- chemistry.chemical_element
02 engineering and technology
010402 general chemistry
01 natural sciences
Analytical Chemistry
Ion
Human health
Limit of Detection
Animals
Humans
Instrumentation
Zebrafish
Spectroscopy
Fluorescent Dyes
Ions
Detection limit
biology
Chemistry
Spectral properties
Mercury
021001 nanoscience & nanotechnology
biology.organism_classification
Fluorescence
Atomic and Molecular Physics, and Optics
0104 chemical sciences
Mercury (element)
Biophysics
Naked eye
0210 nano-technology
HeLa Cells
Subjects
Details
- ISSN :
- 13861425
- Volume :
- 249
- Database :
- OpenAIRE
- Journal :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- Accession number :
- edsair.doi.dedup.....d299e463fe3c47621a6a7631f90e7797