Back to Search
Start Over
Combined trans- and periurethral injections of bulking agents for the treatment of intrinsic sphincter deficiency
- Source :
- International urogynecology journal and pelvic floor dysfunction. 19(5)
- Publication Year :
- 2007
-
Abstract
- The purpose of this study was to compare Contigen combined with Durasphere to Contigen injections alone for the treatment of stress urinary incontinence (SUI) with intrinsic sphincter deficiency (ISD). Subjective and objective incontinence outcomes were compared at 2 weeks and 6 months. We compared rates of urinary retention and future incontinence surgery between groups. Thirty-three women underwent combined injections, and 51 underwent Contigen injections. Two weeks postoperatively, more women in the combined group were cured (72.7 vs. 39.2%, P = 0.003), but this difference diminished at 6 months (33.3 vs. 29.4%, P = 0.70). Retention was more common in the combined group (P = 0.002, odds ratio [OR] = 0.062 [95% confidence interval {CI} = 0.007, 0.52]). Twenty-three women in the Contigen and ten in the combined group underwent subsequent incontinence surgery (P = 0.17, OR = 2.03 [95% CI = 0.80, 5.1]). Combining Contigen and Durasphere injections to treat SUI with ISD does not improve outcomes compared to Contigen injections alone.
- Subjects :
- medicine.medical_specialty
Time Factors
Urology
Urinary Incontinence, Stress
Urinary incontinence
Biocompatible Materials
Injections
Urethra
medicine
Humans
Glucans
Aged
Retrospective Studies
Urinary retention
business.industry
Intrinsic sphincter deficiency
Obstetrics and Gynecology
Odds ratio
Prostheses and Implants
Confidence interval
Surgery
Urodynamics
Treatment Outcome
Durasphere
Female
Collagen
Zirconium
medicine.symptom
business
Follow-Up Studies
Subjects
Details
- Volume :
- 19
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- International urogynecology journal and pelvic floor dysfunction
- Accession number :
- edsair.doi.dedup.....d291f83d1e8917f69a26cae428ae709b