Effects of dietary yeast β-glucan on nutrient digestibility and serum profiles in pre-ruminant Holstein calves

This study aimed to investigate the effects of dietary supplementation of yeast β-glucan on the nutrient digestibility and serum profiles in pre-ruminant Holstein calves. Forty-two neonatal Holstein calves ((39.6±4.2) kg) were randomly allotted to six groups, and each was offered one of the following diets: a basal diet (control) or the basal diet supplemented with 25, 50, 75, 100 or 200 mg of yeast β-glucan kg−1 feed (dry matter basis). The basal diet consisted of a milk replacer and a starter feed. The trial lasted for 56 d. Two digestibility trials were conducted from d 14 to 20 and from d 42 to 48. Blood samples were collected on d 0, 14, 28 and 42 for serum profile analyses. On d 56, three calves from each group were slaughtered, and intestinal samples were collected to assess the villous height, crypt depth and mucosal thickness. Although feed intake was not affected by dietary treatment (P>0.05), the average daily gain (ADG) and gain-to-feed ratios were higher (P0.05). Compared with the control group, supplementation of yeast β-glucan decreased (P0.05). The supplementation of yeast β-glucan stimulated the enzymatic activity of alkaline phosphatase (ALP) (P