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Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor
- Source :
- Chemical Communications. 47:8424
- Publication Year :
- 2011
- Publisher :
- Royal Society of Chemistry (RSC), 2011.
-
Abstract
- The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.
- Subjects :
- Boron Compounds
biology
Chemistry
Electron Spin Resonance Spectroscopy
Metals and Alloys
General Chemistry
Combinatorial synthesis
Combinatorial chemistry
Fluorescence
Catalysis
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
chemistry.chemical_compound
Spectrometry, Fluorescence
Solid-phase synthesis
Immunoglobulin G
Materials Chemistry
Ceramics and Composites
biology.protein
Humans
BODIPY
Antibody
Fluorescent Dyes
Protein Binding
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 47
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....d1e80a33c2c32d30f62bf627590e6c44