Back to Search
Start Over
Comorbidities and healthcare costs and resource use of patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) in the Japan medical data vision database
- Source :
- Journal of Gastroenterology
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Background This study examined demographics, comorbidities and healthcare resource use (HCRU) and costs among Japanese patients with nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Methods We conducted a repeated cross-sectional analysis of the Medical Data Vision (MDV) claims database, from January 2011 to March 2018. Demographics were described at index date and by calendar year; a “NASH” subpopulation included patients with ≥ 1 claim for NASH at any time. Prevalence of pre-specified comorbidities of interest and data-emergent top comorbidities were estimated. All-cause HCRU and costs were quantified by calendar year. Outcomes were compared between 2011 and 2017 using partially overlapping t tests. Results 58,958 patients (mean age 61.6 years; 55.5% male) were included. 1139 patients (2%) were in the NASH subpopulation. At baseline, comorbid cardiovascular disease (69.4%), diabetes (62.1%) and hyperlipidaemia (54.4%) were most prevalent; comorbidity prevalence increased with age. Mean outpatient visits decreased from 9.36 per patient in 2011 to 7.80 in 2017; mean inpatient admissions increased (both p p = 0.552), cost burden shifted from the outpatient to inpatient setting between 2011 and 2017. All-cause healthcare resource use/costs were generally higher for the NASH subgroup compared with the overall population. Conclusions There is a high burden of disease among Japanese NAFLD/NASH patients, including a high prevalence of comorbidities which generally increase with age. Accordingly, substantial all-cause HCRU and costs were incurred.
- Subjects :
- Adult
Male
medicine.medical_specialty
Adolescent
Cost
Population
Comorbidity
Disease
Resource Allocation
Japan
Non-alcoholic Fatty Liver Disease
Diabetes mellitus
Internal medicine
Nonalcoholic fatty liver disease
Prevalence
medicine
Humans
Nonalcoholic steatohepatitis
education
Aged
Retrospective Studies
Original Article—Liver, Pancreas, and Biliary Tract
education.field_of_study
business.industry
Gastroenterology
Health Care Costs
Middle Aged
Hepatology
medicine.disease
Database analysis
Colorectal surgery
Cross-Sectional Studies
Liver
Female
business
Abdominal surgery
Subjects
Details
- ISSN :
- 14355922 and 09441174
- Volume :
- 56
- Database :
- OpenAIRE
- Journal :
- Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....d1d8435fd8a3227281876a55b4480e26