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Delayed mfERG responses in myopia
- Source :
- Vision Research. 46:1221-1229
- Publication Year :
- 2006
- Publisher :
- Elsevier BV, 2006.
-
Abstract
- It has been suggested that changes in the multifocal electroretinogram (mfERG) responses in myopes are primarily due to the increased axial length that accompanies myopia development. We investigated the characteristics of mfERG responses between emmetropes and myopes and determined the contribution of axial length to the mfERG data in 30 subjects (10 emmetropes and 20 myopes) using VERIS I. The amplitude and implicit time of the first positive peak (P1) of the first-order kernel were analyzed. We found that P1 implicit time in myopes was significantly longer by 1.3–3.1ms than that of the emmetropes and this was not explained by the myopes having greater axial lengths than the emmetropes. Axial length contributed to 15% of the implicit time total variance while refractive error accounted for 27%. Delayed mfERG responses observed in myopes were not attributable to the anatomical change that accompanies myopia and may suggest underlying differences in retinal function that result from being myopic.
- Subjects :
- Adult
medicine.medical_specialty
Delayed response
Refractive error
Adolescent
genetic structures
Eye disease
Eye
Retina
Vision disorder
Axial length
Increased axial length
Optics
Ophthalmology
Electroretinography
Myopia
medicine
Humans
Ultrasonography
Analysis of Variance
MfERG
medicine.diagnostic_test
business.industry
Refractive Errors
medicine.disease
eye diseases
Sensory Systems
Case-Control Studies
Linear Models
Retinal function
sense organs
Multifocal electroretinogram
medicine.symptom
Psychology
business
Subjects
Details
- ISSN :
- 00426989
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- Vision Research
- Accession number :
- edsair.doi.dedup.....d1d15d1b3982971798edd62e6e45017f