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A review of nasopharyngeal swab and saliva tests for SARS‐CoV‐2 infection: Disease timelines, relative sensitivities, and test optimization

Authors :
Stanley R. Hamilton
Vadim Mathys
Sophie Yu
Natalie Krieger
Colin Cook
Marylin Roque
Kevin Proudfoot
Yuman Fong
Thomas Gernon
Kash Gokli
Source :
Journal of Surgical Oncology
Publication Year :
2021
Publisher :
Wiley, 2021.

Abstract

Testing is an essential part of containment of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic. This review summarizes studies for SARS‐CoV‐2 infection and testing. Nasopharyngeal samples are best at sensitivity detection, especially in early stages of disease and in asymptomatic individuals. Current swab processing involves a 100‐ to 1000‐fold dilution of the patient sample. Future optimization of testing should focus on using smaller volumes of viral transport media and swab designs to increase comfort and increased viral adhesion.

Details

ISSN :
10969098 and 00224790
Volume :
124
Database :
OpenAIRE
Journal :
Journal of Surgical Oncology
Accession number :
edsair.doi.dedup.....d1c8489dfe7669eb78d94b1864c29ba8
Full Text :
https://doi.org/10.1002/jso.26561