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Precision medicine in food allergy
- Source :
- Current Opinion in Allergy & Clinical Immunology. 18:438-443
- Publication Year :
- 2018
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2018.
-
Abstract
- To familiarize the reader with the concept of precision medicine in food allergy through the most recent insights in the diagnosis, prognosis, and management of the disease.With the advent of omics sciences, a new era is commencing. Food protein allergens characterization and quantification together with the immunoglobulin E epitope mapping will contribute to the diagnosis/prognosis of food allergy and will lead to a better safety assessment of foods. The characterization of biomarkers able to identify specific phenotypes and endotypes will improve the diagnostic accuracy. This together with a better understanding of mechanisms of action of the different therapeutic options will allow the accurate selection of the appropriate patient.In the near future, advances in technologies and data interpretation will allow a better understanding of the pathogenesis of food allergy and the development of a personalized treatment tailored on the specific patient' profile.
- Subjects :
- Proteomics
medicine.medical_treatment
Immunology
MEDLINE
Cross Reactions
Bioinformatics
03 medical and health sciences
0302 clinical medicine
Food allergy
medicine
Humans
Immunology and Allergy
Precision Medicine
Desensitization (medicine)
030201 allergy
business.industry
Food protein
Allergens
Immunoglobulin E
Prognosis
Precision medicine
medicine.disease
Omics
Phenotype
030228 respiratory system
Desensitization, Immunologic
Dietary Proteins
business
Epitope Mapping
Food Hypersensitivity
Subjects
Details
- ISSN :
- 14736322 and 15284050
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Current Opinion in Allergy & Clinical Immunology
- Accession number :
- edsair.doi.dedup.....d1b6d1f1eec9a251bbe50106385c4765
- Full Text :
- https://doi.org/10.1097/aci.0000000000000465