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Precision medicine in food allergy

Authors :
Maurizio Mennini
Carla Riccardi
Alessandro Fiocchi
Rocco Luigi Valluzzi
Stefania Arasi
Source :
Current Opinion in Allergy & Clinical Immunology. 18:438-443
Publication Year :
2018
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2018.

Abstract

To familiarize the reader with the concept of precision medicine in food allergy through the most recent insights in the diagnosis, prognosis, and management of the disease.With the advent of omics sciences, a new era is commencing. Food protein allergens characterization and quantification together with the immunoglobulin E epitope mapping will contribute to the diagnosis/prognosis of food allergy and will lead to a better safety assessment of foods. The characterization of biomarkers able to identify specific phenotypes and endotypes will improve the diagnostic accuracy. This together with a better understanding of mechanisms of action of the different therapeutic options will allow the accurate selection of the appropriate patient.In the near future, advances in technologies and data interpretation will allow a better understanding of the pathogenesis of food allergy and the development of a personalized treatment tailored on the specific patient' profile.

Details

ISSN :
14736322 and 15284050
Volume :
18
Database :
OpenAIRE
Journal :
Current Opinion in Allergy & Clinical Immunology
Accession number :
edsair.doi.dedup.....d1b6d1f1eec9a251bbe50106385c4765
Full Text :
https://doi.org/10.1097/aci.0000000000000465