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Risk Factors for Early Mortality Among Patients with Glioma: A Population-Based Study
- Source :
- World neurosurgery. 136
- Publication Year :
- 2019
-
Abstract
- Objective The present study evaluated the early death and factors associated with early mortality in patients with glioma. Methods The data used for analysis in the present study was extracted from the Surveillance, Epidemiology, and End Results data set. Results A total of 58,700 patients with glioma were enrolled in the present study. The proportion of patient death within 1 month and 3 months after the diagnosis was 9.24% and 19.15% for all patients, respectively. The factors significantly associated with death within 1 month after tumor resection on multivariate analysis included age at diagnosis, year of diagnosis, tumor location, histological features, tumor size, and the absence of gross total resection, radiotherapy, and chemotherapy. We also observed similar findings in the evaluation of the factors associated with 3-month mortality. Conclusion The early deaths rates, including 1 and 3 months after tumor resection in patients with glioma, have decreased slightly during the previous 40 years. The risk factors for early mortality included advanced age, male sex, tumor located in the lateral ventricle, cerebellum, or brainstem, receipt of biopsy only, no chemotherapy or radiotherapy, and specific histopathological types.
- Subjects :
- Oncology
Adult
Male
medicine.medical_specialty
Multivariate analysis
Adolescent
medicine.medical_treatment
Tumor resection
03 medical and health sciences
Young Adult
0302 clinical medicine
Age Distribution
Risk Factors
Internal medicine
Glioma
Epidemiology
Medicine
Humans
Age of Onset
Aged
Aged, 80 and over
Chemotherapy
Tumor size
business.industry
Brain Neoplasms
Mortality, Premature
Middle Aged
medicine.disease
United States
Radiation therapy
Population based study
030220 oncology & carcinogenesis
Surgery
Female
Neurology (clinical)
business
030217 neurology & neurosurgery
SEER Program
Subjects
Details
- ISSN :
- 18788769
- Volume :
- 136
- Database :
- OpenAIRE
- Journal :
- World neurosurgery
- Accession number :
- edsair.doi.dedup.....d16b11aaa9c3a9b8f85fb580fdf738e9