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Carotid intima-media thickness and flow-mediated dilation in obese children with non-alcoholic fatty liver disease
- Source :
- The Turkish Journal of Gastroenterology. 25:92-98
- Publication Year :
- 2015
- Publisher :
- AVES Publishing Co., 2015.
-
Abstract
- Background/Aims: This study aimed to understand the role of non-alcoholic fatty liver disease (NAFLD) in increasing the risk of atherosclerosis in obese pediatric patients. Materials and Methods: The study included 109 obese children (age, 9-15 years) and a control group comprising 44 healthy age- and gender-matched children with normal weight. NAFLD was diagnosed using conventional ultrasound (US) examination. Both right carotid intima-media thickness (CIMT) and flow-mediated dilation (FMD) were assessed in addition to anthropometric measures and serum biochemical parameters, including lipid profile and fasting glucose and insulin levels. Homeostatic model assessment of insulin resistance (HOMA-IR) was calculated as a measure of insulin resistance. Results: Mean age and gender distributions were similar in the obese children and control group (p=0.168 and p=0.705, respectively). Median body mass index standard deviation scores of obese children with grade II-III NAFLD were significantly higher than those of obese children without hepatosteatosis (p
- Subjects :
- Male
medicine.medical_specialty
Adolescent
Carotid Intima-Media Thickness
Severity of Illness Index
Gastroenterology
Body Mass Index
Insulin resistance
Non-alcoholic Fatty Liver Disease
Predictive Value of Tests
Risk Factors
Internal medicine
medicine
Humans
Obesity
Child
the official journal of Turkish Society of Gastroenterology, ss.92-8, 2014 [Torun E., Aydin S., Gokce S., Ozgen I. T. , Donmez T., Cesur Y., -Carotid intima-media thickness and flow-mediated dilation in obese children with non-alcoholic fatty liver disease.-, The Turkish journal of gastroenterology]
Triglycerides
medicine.diagnostic_test
business.industry
Cholesterol, HDL
Fatty liver
Alanine Transaminase
Cholesterol, LDL
Atherosclerosis
medicine.disease
digestive system diseases
Vasodilation
Endocrinology
Intima-media thickness
Case-Control Studies
Homeostatic model assessment
Female
Median body
Insulin Resistance
Steatosis
Lipid profile
business
Body mass index
Subjects
Details
- ISSN :
- 21485607 and 13004948
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- The Turkish Journal of Gastroenterology
- Accession number :
- edsair.doi.dedup.....d1338b67a72f0100fc2c0f49b452c11f