Back to Search
Start Over
Effects of smoking on central blood pressure and pressure amplification in hypertension of the young
- Publication Year :
- 2016
-
Abstract
- The aim of this study was to investigate the effect of cigarette smoking on peripheral and central blood pressure (BP) in a group of young stage I hypertensives. A total of 344 untreated subjects from the HARVEST study were examined (mean age 37±10 years). Patients were divided into three groups based on smoking status: non-smokers, light smokers (⩽5 cigarettes/day) and moderate-to-heavy smokers (>5 cigarettes/day); and into three groups by age: 18–29, 30–39 and ⩾40 years. Central BP measurements and augmentation index (AIx) were calculated from brachial pressure waveform, with applanation tonometry, by means of the Specaway DAT System plus a Millar tonometer. The central waveform was derived from peripheral BP using the same software system of the SphygmoCor System pulse wave analysis. In addition, two indirect measurements of arterial stiffness were calculated: pulse pressure (PP) and systolic BP amplification. Central systolic BP and PP were higher in smokers than in non-smokers (systolic BP: 121.9±13.1 mmHg in non-smokers, 127.2±16.5 mmHg in light smokers, 126.7±15.3 mmHg in those who smoked >5 cigarettes/day, p=0.009; PP: 37.7±9.8 mmHg, 41.5±13.1 mmHg, 41.9±10.5 mmHg, respectively, p=0.005). Lower systolic BP amplification ( p
- Subjects :
- Adult
Male
medicine.medical_specialty
hypertension
Adolescent
Brachial Artery
Manometry
central blood pressure
Pulse Wave Analysis
030204 cardiovascular system & hematology
arterial stiffness
smoking
youth
Young Adult
03 medical and health sciences
0302 clinical medicine
Risk Factors
Internal medicine
medicine.artery
medicine
Humans
Arterial Pressure
Prospective Studies
030212 general & internal medicine
Young adult
Brachial artery
Prospective cohort study
Analysis of Variance
business.industry
Age Factors
Middle Aged
medicine.disease
Peripheral
Pulse pressure
Cross-Sectional Studies
Blood pressure
Italy
Anesthesia
Disease Progression
Cardiology
Arterial stiffness
Female
Analysis of variance
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....d11552d77dce80d85f34d1e668ad60b6