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Prospective Evaluation of Factors Affecting the Safety and Efficacy of Perclose Proglide Vascular Closure Device in Neurovascular Interventions
- Source :
- Neurology India. 67:1305
- Publication Year :
- 2019
- Publisher :
- Medknow, 2019.
-
Abstract
- Background: Most of the neurointerventional procedures use various anticoagulants, antiplatelets, and fibrinolytic drugs, and it can predispose arterial access site complications. Safe and efficient closure arteriotomy site has extreme importance in reducing the morbidity. Percutaneous vascular closure devices (VCDs) enable us to close the arteriotomy sites. In this prospective study, we evaluated the factors affecting the safety and efficacy of Perclose ProGlide VCD in neurovascular interventions. Materials and Methods: In this prospective study, we have evaluated the safety and efficacy of 327 Perclose ProGlide devices deployed in 217 patients who underwent various neurointerventions in our institute from October 2014 to October 2016. Time to achieve hemostasis (TAH) was calculated for various groups and the statistical significance of mean values between groups was estimated. Results: Out of the 327 Perclose ProGlide deployed, complication rate was 0.91% and the mean TAH was 77.14 s. Assessment of TAH mean value showed statistically significant prolongation of TAH in obesity and those with larger arterial sheaths. Age, sex, post-heparin ACT, peri-procedure medications, and type of diseases had no significant role in increasing TAH. The evaluation also showed the presence of a learning curve in using this device. Conclusion: Perclose ProGlide VCD is safe and effective in closing the arteriotomy after neurointerventions. Obesity and larger arterial sheaths are independent factors prolonging the TAH. Learning curve associated with this device mildly increases the hemostatic time and device-related complications.
- Subjects :
- Adult
Male
medicine.medical_specialty
Percutaneous
medicine.medical_treatment
Psychological intervention
Arteriotomy
Arterial Access Site
Neurosurgical Procedures
030218 nuclear medicine & medical imaging
03 medical and health sciences
0302 clinical medicine
medicine
Humans
Vascular closure device
Prospective cohort study
Aged
business.industry
Middle Aged
Neurovascular bundle
Surgery
Femoral Artery
Neurology
Hemostasis
Female
Neurology (clinical)
business
Vascular Surgical Procedures
Vascular Closure Devices
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 00283886
- Volume :
- 67
- Database :
- OpenAIRE
- Journal :
- Neurology India
- Accession number :
- edsair.doi.dedup.....d101b50b804ca91a9742a56f2c7e058d