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Incidence rate and risk factors for radiographic hip osteoarthritis in Japanese men and women: a 10-year follow-up of the ROAD study
- Source :
- Osteoarthritis and Cartilage. 28:182-188
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- To investigate the incidence and progression rate of radiographic hip osteoarthritis (OA) and its risk factors in Japanese men and women using a large-scale population of a nationwide cohort study, Research on Osteoarthritis/osteoporosis Against Disability (ROAD).From the baseline survey of the ROAD study, 2,975 participants (1,043 men and 1,932 women) aged 23-94 years (mean, 70.2 years) living in urban, mountainous, and coastal communities were followed up with hip radiography at 3, 7, and 10 years (mean follow-up, 7.1 years). Radiographs were scored using the Kellgren/Lawrence (K/L) grading system, and radiographic hip OA was defined as K/L ≥ 2. The incidence and progression rate of hip OA were examined. Acetabular dysplasia was defined as a central-edge angle20°. Cox's proportional hazard model was used to assess risk factors for incident and progressive radiographic hip OA.The incidence rate of radiographic hip OA was 5.6/1,000 person-years and 8.4/1,000 person-years in men and women, respectively. The progression rate of hip OA was 2.2/1,000 person-years and 6.0/1,000 person-years in men and women, respectively. The significant risk factors for incident hip OA were age, obesity, and acetabular dysplasia at baseline (hazard risk [HR] 1.05, 95% confidence interval [CI] 1.03-1.08; 1.78, 1.10-2.75; 2.06, 1.30-3.17, respectively). The significant risk factors for progressive hip OA were baseline hip pain and acetabular dysplasia (HR 5.68, 95%CI 1.07-22.61; 14.78, 3.66-56.06, respectively).Continued longitudinal surveys of the ROAD study will contribute to knowledge about and potential prevention of incident and progressive hip OA.
- Subjects :
- Adult
Male
musculoskeletal diseases
0301 basic medicine
medicine.medical_specialty
Population
Osteoporosis
Biomedical Engineering
Osteoarthritis
Osteoarthritis, Hip
Young Adult
03 medical and health sciences
0302 clinical medicine
Japan
Rheumatology
Risk Factors
Internal medicine
Humans
Medicine
Orthopedics and Sports Medicine
Obesity
education
Aged
Proportional Hazards Models
Aged, 80 and over
030203 arthritis & rheumatology
education.field_of_study
business.industry
Incidence
Incidence (epidemiology)
Age Factors
Acetabulum
Middle Aged
medicine.disease
Confidence interval
Acetabular dysplasia
030104 developmental biology
Disease Progression
Developmental Dysplasia of the Hip
Female
business
Follow-Up Studies
Cohort study
Subjects
Details
- ISSN :
- 10634584
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Osteoarthritis and Cartilage
- Accession number :
- edsair.doi.dedup.....d0e37ee6f106012b1c33703f31ccd15e