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Passive and active markers of cortical excitability in epilepsy

Authors :
Ramantani, Georgia
Westover, M Brandon
Gliske, Stephen
Sarnthein, Johannes
Sarma, Sridevi
Wang, Yujiang
Baud, Maxime O
Stacey, William C
Conrad, Erin C
University of Zurich
Stacey, William C
Publication Year :
2023
Publisher :
Wiley, 2023.

Abstract

EEG has been the primary diagnostic tool in clinical epilepsy for nearly a century. Its review is performed using qualitative clinical methods that have changed little over time. However, the intersection of higher resolution digital EEG and analytical tools developed in the last decade invites a re-exploration of relevant methodology. In addition to the established spatial and temporal markers of spikes and high frequency oscillations, novel markers involving advanced post-processing and active probing of the interictal EEG are gaining ground. This review provides an overview of the EEG-based passive and active markers of cortical excitability in epilepsy and of the techniques developed to facilitate their identification. Several different emerging tools are discussed in the context of specific EEG applications and the barriers we must overcome to translate these tools into clinical practice.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....d0b8b94fd56e9c12bdfe8f69b0b6f816
Full Text :
https://doi.org/10.48350/179897