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Quantitative power Doppler signal assessment in the subchondral bone region of the metacarpophalangeal joint is an effective predictor of radiographic progression in the hand of rheumatoid arthritis: a pilot study
- Source :
- Rheumatology International. 39:1413-1421
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Ultrasonography is useful for assessment of synovitis in the hand of rheumatoid arthritis (RA) patients. The aim of this study was to investigate the predictive value of the quantitative power Doppler (PD) signal assessment in the subchondral bone region of the metacarpophalangeal (MCP) joint in patients with RA showing radiographic progression of the hand by comparing with those of previously reported scoring systems. Twenty-two patients (20 women) with RA who underwent power Doppler ultrasonography (PDUS) of the bilateral one to five MCP joints at baseline were included in the study. Radiography of both hands was performed at baseline and at 1 year. PDUS of the synovial space was evaluated according to semi-quantitative scoring (0–3) and quantitative measurement (0–100%). The PD signal in the subchondral bone region was qualitatively (0, 1) and quantitatively (mm2) assessed. The performance of PDUS assessment was compared using the area under the curve (AUC) of the receiver operating characteristic (ROC) curve and the risk ratio (RR). As a predictor for radiographic progression, the quantitative PD signal assessment in the subchondral bone region (AUC = 0.842, p
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
Radiography
Immunology
Arthritis
Pilot Projects
Severity of Illness Index
Arthritis, Rheumatoid
Metacarpophalangeal Joint
03 medical and health sciences
0302 clinical medicine
Vascularity
Rheumatology
Predictive Value of Tests
Synovitis
Internal medicine
medicine
Humans
Immunology and Allergy
030212 general & internal medicine
Bone
Ultrasonography
Aged
Retrospective Studies
Observer Variation
030203 arthritis & rheumatology
Receiver operating characteristic
business.industry
Reproducibility of Results
Ultrasonography, Doppler
Metacarpophalangeal joint
Middle Aged
Hand
medicine.disease
medicine.anatomical_structure
Antirheumatic Agents
Rheumatoid arthritis
Disease Progression
Female
medicine.symptom
Nuclear medicine
business
Subjects
Details
- ISSN :
- 1437160X and 01728172
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Rheumatology International
- Accession number :
- edsair.doi.dedup.....d07674d13b79837bd5a59e5deb29c912