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Seroprevalence of Filovirus Infection of Rousettus aegyptiacus Bats in Zambia
- Source :
- The Journal of Infectious Diseases.
- Publication Year :
- 2018
- Publisher :
- Oxford University Press (OUP), 2018.
-
Abstract
- Bats are suspected to play important roles in the ecology of filoviruses, including ebolaviruses and marburgviruses. A cave-dwelling fruit bat, Rousettus aegyptiacus, has been shown to be a reservoir of marburgviruses. Using an enzyme-linked immunosorbent assay with the viral glycoprotein antigen, we detected immunoglobulin G antibodies specific to multiple filoviruses in 158 of 290 serum samples of R aegyptiacus bats captured in Zambia during the years 2014-2017. In particular, 43.8% of the bats were seropositive to marburgvirus, supporting the notion that this bat species continuously maintains marburgviruses as a reservoir. Of note, distinct peaks of seropositive rates were repeatedly observed at the beginning of rainy seasons, suggesting seasonality of the presence of newly infected individuals in this bat population. These data highlight the need for continued monitoring of filovirus infection in this bat species even in countries where filovirus diseases have not been reported.
- Subjects :
- Male
0301 basic medicine
Population
Zambia
Zoology
Biology
Antibodies, Viral
03 medical and health sciences
Seroepidemiologic Studies
Chiroptera
Filoviridae Infections
Animals
Immunology and Allergy
Seroprevalence
education
Viral immunology
Disease Reservoirs
Glycoproteins
education.field_of_study
Viral glycoprotein
Filoviridae
Marburgvirus
biology.organism_classification
Serum samples
Filovirus
030104 developmental biology
Infectious Diseases
Immunoglobulin G
Fruit bats
biology.protein
ELISA
Female
Antibody
Rousettus
Subjects
Details
- ISSN :
- 15376613 and 00221899
- Database :
- OpenAIRE
- Journal :
- The Journal of Infectious Diseases
- Accession number :
- edsair.doi.dedup.....d070151cdf7029ce75124840295f9e38