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Adult neurogenesis and the future of the rejuvenating brain circuits
- Source :
- Neuron, Neuron, Elsevier, 2015, 86 (2), pp.387-401. ⟨10.1016/j.neuron.2015.01.002⟩, Neuron, 2015, 86 (2), pp.387-401. ⟨10.1016/j.neuron.2015.01.002⟩
- Publication Year :
- 2015
- Publisher :
- HAL CCSD, 2015.
-
Abstract
- International audience; For a long time, the mammalian brain has been perceived to be a static organ. However, the discovery of adult neurogenesis in most mammalian species, including humans, monkeys, and rodents, has disrupted this view. As this continuous regeneration has an effect on established behavioral patterns, it holds promising therapeutic potential. However, before harnessing this potential regenerative power, we must understand what effects new neurons have on existing brain circuits. Ongoing research contributes to several important steps toward bridging the gap between adult-born neurons, circuits, and behavior. The study of adult neurogenesis in different neurogenic regions from a systems neuroscience perspective will pave the way to understanding how it supports adaptive behavior and why its dysfunction correlates with some human brain disorders.
- Subjects :
- Adult
MESH: Forecasting
Biomedical Research
MESH: Hippocampus
Neurogenesis
[SDV]Life Sciences [q-bio]
MESH: Brain Diseases
MESH: Neurons
MESH: Mental Recall
MESH: Rejuvenation
Biology
Regenerative Medicine
Hippocampus
medicine
Humans
Rejuvenation
MESH: Neuronal Plasticity
Neurons
Systems neuroscience
Adaptive behavior
Brain Diseases
Neuronal Plasticity
MESH: Humans
General Neuroscience
Regeneration (biology)
MESH: Biomedical Research
[SCCO.NEUR]Cognitive science/Neuroscience
MESH: Adult
Human brain
Mammalian brain
MESH: Neurogenesis
Chromosome Pairing
medicine.anatomical_structure
MESH: Chromosome Pairing
MESH: Nerve Net
MESH: Regenerative Medicine
Mental Recall
Nerve Net
Neuroscience
Forecasting
Subjects
Details
- Language :
- English
- ISSN :
- 08966273
- Database :
- OpenAIRE
- Journal :
- Neuron, Neuron, Elsevier, 2015, 86 (2), pp.387-401. ⟨10.1016/j.neuron.2015.01.002⟩, Neuron, 2015, 86 (2), pp.387-401. ⟨10.1016/j.neuron.2015.01.002⟩
- Accession number :
- edsair.doi.dedup.....cffeb4389868286d0693571d1453afd5
- Full Text :
- https://doi.org/10.1016/j.neuron.2015.01.002⟩