Back to Search
Start Over
Presence and Persistence of Zika Virus RNA in Semen, United Kingdom, 2016
- Source :
- Emerging Infectious Diseases, Vol 23, Iss 4, Pp 611-615 (2017), Emerging Infectious Diseases
- Publication Year :
- 2017
- Publisher :
- Centers for Disease Control and Prevention (CDC), 2017.
-
Abstract
- Zika virus RNA has been detected in semen collected several months after onset of symptoms of infection. Given the potential for sexual transmission of Zika virus and for serious fetal abnormalities resulting from infection during pregnancy, information regarding the persistence of Zika virus in semen is critical for advancing our understanding of potential risks. We tested serial semen samples from symptomatic male patients in the United Kingdom who had a diagnosis of imported Zika virus infection. Among the initial semen samples from 23 patients, Zika virus RNA was detected at high levels in 13 (56.5%) and was not detected in 9 (39.1%); detection was indeterminate in 1 sample (4.4%). After symptomatic infection, a substantial proportion of men have detectable Zika virus RNA at high copy numbers in semen during early convalescence, suggesting high risk for sexual transmission. Viral RNA clearance times are not consistent and can be prolonged.
- Subjects :
- Adult
Male
0301 basic medicine
Microbiology (medical)
Sexual transmission
Epidemiology
media_common.quotation_subject
vector-borne infections
lcsh:Medicine
Semen
mosquitoborne
lcsh:Infectious and parasitic diseases
Zika virus
03 medical and health sciences
Zika
0302 clinical medicine
flavivirus
medicine
Humans
viruses
lcsh:RC109-216
030212 general & internal medicine
media_common
Pregnancy
Fetus
biology
Zika Virus Infection
Research
Convalescence
lcsh:R
Presence and Persistence of Zika Virus RNA in Semen, United Kingdom, 2016
RNA
semen
persistence
Zika Virus
medicine.disease
biology.organism_classification
Virology
United Kingdom
sexual transmission
Flavivirus
030104 developmental biology
Infectious Diseases
RNA, Viral
Subjects
Details
- ISSN :
- 10806059 and 10806040
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Emerging Infectious Diseases
- Accession number :
- edsair.doi.dedup.....cf9ab5bef69cb30c57b801ab407612d7