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Clinical features of patients who had two COVID-19 episodes: a European multicentre case series
- Source :
- Journal of Internal Medicine, Journal of Internal Medicine, Wiley, 2021, 290 (2), pp.421-429. ⟨10.1111/joim.13259⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- International audience; Objective: To investigate the clinical features of patients who had two demonstrated coronavirus disease 2019 (COVID-19) episodes. Methods: Data of patients with both COVID-19 episodes were recruited from 22 March to 27 December 2020. The following outcomes were studied: epidemiological, comorbidities, prevalence and severity of general and otolaryngological symptom, olfactory, aroma, and gustatory dysfunctions. A comparison between first and second episodes was performed. Results: Forty-five patients reported having two confirmed COVID-19 episodes. The majority of patients had mild infections in both episodes. The second clinical episode was significantly similar to the first. The symptom duration of the second episode was shorter than the first. The occurrence of loss of smell was unpredictable from the first to the second episode. Conclusion: The recurrence of COVID-19 symptoms is associated with a similar clinical picture than the first episode in patients with initial mild-to-moderate COVID episode. The pathophysiological mechanisms underlying the development of second episode remain uncertain and may involve either true reinfection or virus reactivation from sanctuaries.
- Subjects :
- 0301 basic medicine
myalgia
Male
Pediatrics
[SDV]Life Sciences [q-bio]
severity
Comorbidity
030204 cardiovascular system & hematology
Severity of Illness Index
SARS‐CoV‐2
clinical
Olfaction Disorders
Taste Disorders
0302 clinical medicine
Olfaction Disorder
Epidemiology
Medicine
First episode
Brief Report
Headache
symptom
3. Good health
Europe
Hospitalization
Taste disorder
Female
medicine.symptom
Human
Adult
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Fever
reinfection
03 medical and health sciences
COVID‐19
Severity of illness
Internal Medicine
Humans
Series (stratigraphy)
business.industry
SARS-CoV-2
COVID-19
Myalgia
medicine.disease
030104 developmental biology
Dyspnea
Asthenia
Immunoglobulin G
symptoms
Brief Reports
business
Subjects
Details
- Language :
- English
- ISSN :
- 09546820 and 13652796
- Database :
- OpenAIRE
- Journal :
- Journal of Internal Medicine, Journal of Internal Medicine, Wiley, 2021, 290 (2), pp.421-429. ⟨10.1111/joim.13259⟩
- Accession number :
- edsair.doi.dedup.....cf817c3133e63805c0b7565223393570