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Phlegmonous Gastritis in a Patient With Myeloid Sarcoma
- Source :
- Applied Immunohistochemistry & Molecular Morphology. 17:458-462
- Publication Year :
- 2009
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2009.
-
Abstract
- Phlegmonous gastritis is a rare acute bacterial infection of the gastric wall with an extremely high mortality rate. Early diagnosis is crucial for immediate treatment that could improve the outcomes. Here we report a case in which a patient with underlying chronic myelomonocytic leukemia was diagnosed with phlegmonous gastritis on biopsy. This 57-year-old man presented with shortness of breath and intermittent upper quadrant abdominal pain for 4 days. Laboratory tests showed markedly increased white blood cell. A diagnosis of chronic myelomonocytic leukemia was made based on a peripheral blood smear and flow cytometry. Gastric biopsy showed suppurative inflammation in the submucosal region, prompting the diagnosis of phlegmonous gastritis. The patient was given empirical antibiotic treatment, and the white blood cell decreased dramatically. Surgical intervention was discussed but deferred. Despite continued antibiotics treatment, the patient died. The limited autopsy confirmed the diagnosis of phlegmonous gastritis. Immunohistochemical studies further revealed the occurrence of myeloid sarcoma that involved the gastrointestinal tract.
- Subjects :
- Male
medicine.medical_specialty
Abdominal pain
Histology
Biopsy
Chronic myelomonocytic leukemia
Gastroenterology
Immunophenotyping
Pathology and Forensic Medicine
Quadrant (abdomen)
Internal medicine
White blood cell
medicine
Myeloid sarcoma
Humans
Sarcoma, Myeloid
medicine.diagnostic_test
business.industry
Middle Aged
medicine.disease
Immunohistochemistry
Medical Laboratory Technology
medicine.anatomical_structure
Gastritis
Sarcoma
medicine.symptom
business
Subjects
Details
- ISSN :
- 15412016
- Volume :
- 17
- Database :
- OpenAIRE
- Journal :
- Applied Immunohistochemistry & Molecular Morphology
- Accession number :
- edsair.doi.dedup.....cf7352e97a9120d948a86753ef81391b