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Sox9 affects cell survival in a chondrosarcoma cell line via Bcl-2- and Survivin-mediated mechanisms

Authors :
Stöckl, Sabine
Göttl, Claudia
Hillmann, Axel
Grässel, Susanne
Source :
Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2019); 20191022-20191025; Berlin; DOCAB41-370 /20191022/
Publication Year :
2019
Publisher :
German Medical Science GMS Publishing House; Düsseldorf, 2019.

Abstract

Objectives: Chondrosarcoma is the second most common form of primary malignant bone tumors overall, but is the most common form in adults. Accumulating evidence from recent studies point to a critical role of Sox9, the master transcription factor for chondrogenesis, as a proto-oncogene in plenty of [for full text, please go to the a.m. URL]<br />Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2019)

Details

Language :
English
Database :
OpenAIRE
Journal :
Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2019); 20191022-20191025; Berlin; DOCAB41-370 /20191022/
Accession number :
edsair.doi.dedup.....cf29984496264e167ce20d6c08120bf6