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Additional file 7: of PCBP1 depletion promotes tumorigenesis through attenuation of p27Kip1 mRNA stability and translation

Authors :
Hongshun Shi
Li, Hui
Ronghua Yuan
Guan, Wen
Xiaomei Zhang
Shaoyang Zhang
Wenliang Zhang
Tong, Fang
Li, Li
Zhihong Song
Changwei Wang
Shulan Yang
Haihe Wang
Publication Year :
2018
Publisher :
figshare, 2018.

Abstract

Figure S5. p27 mRNA stabilized by PCBP1. The half-life of p27 mRNA was derived from the decay curve plotted from the Fig. 6g and h. Linear regression equation in A: PCBP1, y = − 0.0096× + 0.998,R2 = 0.99; GFP, y = − 0.058× + 0.9844, R2 = 0.9865; B: PCBP1 KD, y = − 0.0749× + 0.965, R2 = 0.9607; GFP, y = − 0.0749× + 0.9677, R2 = 0.9387. (PPT 309 kb)

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....cf2480f187c0f9e8a4296b97baf02a3e
Full Text :
https://doi.org/10.6084/m9.figshare.6944957