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Gastroprotective Effect and Antioxidant Properties of DifferentLaurus nobilisL. Leaf Extracts

Authors :
Gabbriella Innocenti
Maria Clelia Guerra
Ester Speroni
Paolo Govoni
Rinaldo Cervellati
Stefano Dall'Acqua
Emanuela Greco
Speroni E.
Cervellati R.
Dall'Acqua S.
Guerra M.C.
Greco E.
Govoni P.
Innocenti G.
Source :
Journal of Medicinal Food. 14:499-504
Publication Year :
2011
Publisher :
Mary Ann Liebert Inc, 2011.

Abstract

Laurus nobilis L. (Family Lauraceae) is an evergreen tree widely distributed in the Mediterranean area and Europe. It is used in folk medicine of different countries as a stomachic and carminative as well as in treatment of gastric diseases. Extracts obtained with different methods (methanol and chloroform) from laurel leaves were evaluated for their gastroprotective activities in the rat. The antioxidant capacity of the different extracts has been also measured in vitro. In order to confirm the activities investigated, histological observations were performed. The gastric damage was significantly reduced by all extracts administered. The more effective protection was produced by chloroformic and methanolic crude extracts. The results obtained after oral administration of L. nobilis leaf extracts are in good agreement with their antioxidant capacity, confirming the relationship between pharmacological efficacy and antiradical activity. Histological evidences confirm the results evaluated with the animal procedures.

Details

ISSN :
15577600 and 1096620X
Volume :
14
Database :
OpenAIRE
Journal :
Journal of Medicinal Food
Accession number :
edsair.doi.dedup.....cf20f815f3ae5a1d054cf7abdf3e1fce
Full Text :
https://doi.org/10.1089/jmf.2010.0084