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Is Sacral Nerve Modulation a Good Option for Fecal Incontinence in Men?

Authors :
B. Trilling
Anne-Marie Leroi
Guillaume Meurette
Laurent Siproudhis
Charlène Brochard
Paul-Antoine Lehur
Valérie Bridoux
Elsa Lambrescak
Jean-Luc Faucheron
Vincent Wyart
Isabelle Etienney
Henri Damon
Igor Sielezneff
Diane Mege
François Mion
Centre d'Investigation Clinique [Rennes] (CIC)
Université de Rennes 1 (UR1)
Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)
Assistance Publique - Hôpitaux de Marseille (APHM)
Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN)
Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
Nutrition, inflammation et dysfonctionnement de l'axe intestin-cerveau (ADEN)
Université de Rouen Normandie (UNIROUEN)
Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Institute for Research and Innovation in Biomedicine (IRIB)
Normandie Université (NU)-Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Normandie Université (NU)
Service de chirurgie digestive [CHU Rouen]
CHU Rouen
Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN)
Centre hospitalier universitaire de Nantes (CHU Nantes)
Hospices Civils de Lyon (HCL)
Groupe Hospitalier Diaconesses Croix Saint-Simon
Gestes Medico-chirurgicaux Assistés par Ordinateur (TIMC-IMAG-GMCAO)
Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG)
Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])
Centre Hospitalier Universitaire [Grenoble] (CHU)
UNIROUEN - UFR Santé (UNIROUEN UFR Santé)
Normandie Université (NU)-Normandie Université (NU)
Centre d'Investigation Clinique [CHU Rouen] (CIC Rouen)
Hôpital Charles Nicolle [Rouen]-CHU Rouen
Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Service de physiologie digestive, urinaire, respiratoire et de l'exercice [CHU Rouen]
Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)
Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM)
Hôpital Charles Nicolle [Rouen]
Normandie Université (NU)-Normandie Université (NU)-CHU Rouen
Source :
Neuromodulation, Neuromodulation, Wiley, 2019, 22 (6), pp.745-750. ⟨10.1111/ner.13017⟩, Neuromodulation, 2019, 22 (6), pp.745-750. ⟨10.1111/ner.13017⟩
Publication Year :
2019
Publisher :
HAL CCSD, 2019.

Abstract

International audience; Objective - The objective was to assess the efficacy and the safety of sacral nerve modulation (SNM) in men with fecal incontinence (FI) compared with those of SNM in women. Method - Prospectively collected data from patients from seven tertiary colorectal units who underwent an implant procedure between January 2010 and December 2015 were reviewed retrospectively. Outcomes and surgical revision and definitive explantation rates were compared between men and women. Results - A total of 469 patients (60 men [12.8%]; mean age = 61.4 ± 12.0 years) were included in the study, 352 (78.1%) (31 men [8.8%]) of whom received a permanent implant. The ratio of implanted/tested men was significantly lower than the ratio of implanted/tested women (p = 0.0004). After a mean follow-up of 3.4 ± 1.9 years, the cumulative successful treatment rates tended to be less favorable in men than in women (p = 0.0514): 88.6% (75.6-95.1), 75.9% (60.9-86.4), 63.9% (48.0-77.3), and 43.9% (26.7-62.7) at one, two, three, and five years, respectively, in men; 92.0% (89.1-94.2), 84.2% (80.3-87.4), 76.8% (72.3-80.7), and 63.6% (57.5-69.3) at one, two, three, and five years, respectively, in women. The revision rate for infection and the definitive explantation rate for infection were higher in men than in women (p = 0.0001 and p = 0.0024, respectively). Conclusion - Both short- and long-term success rates of SNM for FI were lower in men than in women. The revision and definitive explantation for long-term infection rates were significantly higher in men.

Details

Language :
English
ISSN :
10947159 and 15251403
Database :
OpenAIRE
Journal :
Neuromodulation, Neuromodulation, Wiley, 2019, 22 (6), pp.745-750. ⟨10.1111/ner.13017⟩, Neuromodulation, 2019, 22 (6), pp.745-750. ⟨10.1111/ner.13017⟩
Accession number :
edsair.doi.dedup.....cf0a2be421e3461bc3b1af17dbea891b
Full Text :
https://doi.org/10.1111/ner.13017⟩