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Bariatric Surgery Is Efficacious and Improves Access to Transplantation for Morbidly Obese Renal Transplant Candidates
- Source :
- Obesity Surgery. 29:2373-2380
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- The surgical risk of morbidly obese patients is high and even higher for kidney transplant candidates. A BMI > 35–40 kg/m2 is often a contraindication for that surgery. The safety, feasibility, and outcome of bariatric surgery for those patients are inconclusive. We conducted a retrospective chart review of prospectively collected data on morbidly obese renal transplant candidates who underwent laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB) in our institution between January 2009 and September 2017. The reported outcome included body weight and graft status after a mean follow-up of 47 months (range 0.5–5 years). Twenty-four patients (8 females, 16 males, average age 54 years, average preoperative BMI 41 kg/m2 [range 35–51]) underwent LSG (n = 17) or LRYGB (n = 7). Sixteen of them (67%) proceeded to kidney transplantation. Of the 8 pre-transplant and post-bariatric surgery patients, 5 are on the waitlist, and 2 patients died (one of staple line leakage, and one from sepsis unrelated to the bariatric surgery). The average time from bariatric surgery to transplantation was 1.5 years (range 1 month to 4.3 years). The average pre-transplantation BMI was 28 kg/m2 (range 19–36). The mean percentage of excess weight loss was 66% (n = 21), and the total percentage of weight loss was 29% (n = 21). Comorbidities (type 2 diabetes, hypertension, and dyslipidemia) improved significantly following both surgical approaches. LSG and LRYGB appear to effectively address obesity issues before kidney transplantation and improve surgical access. Morbidly obese transplant candidates would benefit from prior bariatric surgery.
- Subjects :
- Male
medicine.medical_specialty
Waiting Lists
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Gastric Bypass
030209 endocrinology & metabolism
Type 2 diabetes
Body Mass Index
End stage renal disease
03 medical and health sciences
0302 clinical medicine
Gastrectomy
Weight loss
Weight Loss
medicine
Humans
Contraindication
Kidney transplantation
Dialysis
Retrospective Studies
Nutrition and Dietetics
business.industry
Middle Aged
medicine.disease
Kidney Transplantation
Obesity, Morbid
Surgery
Transplantation
Female
030211 gastroenterology & hepatology
medicine.symptom
business
Dyslipidemia
Subjects
Details
- ISSN :
- 17080428 and 09608923
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Obesity Surgery
- Accession number :
- edsair.doi.dedup.....cf03bfe1ed9408c985b6bf1fb6ee9e1c