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Expanding DNA nanomachine functionality through binding-induced DNA output for application in clinical diagnosis
- Source :
- Chemical Communications. 55:3610-3613
- Publication Year :
- 2019
- Publisher :
- Royal Society of Chemistry (RSC), 2019.
-
Abstract
- Herein, we describe two homogeneous conversion systems that can convert protein recognition into the release of predesigned output DNA for the activation of DNA nanomachines. With high conversion efficiency, this strategy allows us to initiate DNA nanomachines to respond to any proteins, opening up the possibility of applying DNA nanomachines in clinical practice.
- Subjects :
- 010405 organic chemistry
Metals and Alloys
Proteins
DNA
General Chemistry
Computational biology
010402 general chemistry
01 natural sciences
Catalysis
Nanostructures
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Clinical Practice
chemistry.chemical_compound
chemistry
Homogeneous
Clinical diagnosis
Materials Chemistry
Ceramics and Composites
Protein recognition
Humans
Nanotechnology
Subjects
Details
- ISSN :
- 1364548X and 13597345
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Chemical Communications
- Accession number :
- edsair.doi.dedup.....cededc8e8ba6d44981e40aacd263a21e