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Outcome of live and deceased donor renal transplantation in patients aged ≥55 years: A single-center experience
- Source :
- Indian Journal of Nephrology, Vol 24, Iss 1, Pp 9-14 (2014), Indian Journal of Nephrology
- Publication Year :
- 2014
- Publisher :
- Wolters Kluwer Medknow Publications, 2014.
-
Abstract
- Renal transplantation (RTx) has now become an accepted therapeutic modality of choice for elderly ESRD patients. This single-center study was undertaken to evaluate the outcome of RTx in ESRD patients ≥55 years. A total of 103 patients underwent RTx 79 living related living donors [LD], 24 deceased donors [DD]) at our center. Post-transplant immunosuppression consisted of calcineurin inhibitor-based regimen. The mean donor age was 58.3 years in the LD group and 59.5 years in the DD group. Male recipients constituted 92% in LD and 75% in DD group. In living donor renal transplantation, 1- and 5-year patient survival was 93% and 83.3% respectively and death-censored graft survival was 97.3% and 92.5% respectively. There were 12.6% biopsy proven acute rejection (BPAR) episodes and 12.6% patients were lost, mainly due to infections. In deceased donor renal transplantation, 1- and 5-year patient survival was 79.1% and 74.5% respectively and death-censored graft survival was 95.8% and 85.1% respectively. There were 12.5% BPAR episodes and 25% of patients were lost, mainly due to infections. RTx in ESRD (≥55 years) patients has acceptable patient and graft survival if found to have cardiac fitness and therefore should be encouraged.
- Subjects :
- Deceased donor
medicine.medical_specialty
end-stage renal disease
medicine.diagnostic_test
business.industry
medicine.medical_treatment
Immunosuppression
Single Center
urologic and male genital diseases
lcsh:Diseases of the genitourinary system. Urology
lcsh:RC870-923
End stage renal disease
Surgery
Calcineurin
Transplantation
transplantation in elderly
Regimen
Nephrology
Deceased donor renal transplantation
Biopsy
Medicine
Original Article
business
live donor renal transplantation
Subjects
Details
- Language :
- English
- ISSN :
- 19983662 and 09714065
- Volume :
- 24
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Indian Journal of Nephrology
- Accession number :
- edsair.doi.dedup.....cedb3d9ee8ac2cb56cfdb59b82bcc842