Back to Search
Start Over
Development of an analytical methodology using Fourier transform mass spectrometry to discover new structural analogs of wine natural sweeteners
- Source :
- Analytica Chimica Acta, Analytica Chimica Acta, Elsevier Masson, 2015, 853, pp.425-434. ⟨10.1016/j.aca.2014.10.039⟩
- Publication Year :
- 2015
-
Abstract
- International audience; Volatile and non-volatile molecules are directly responsible for the thrill and excitement provided by wine-tasting. Their elucidation requires powerful analytical techniques and innovative methodologies. In a recent work, two novel sweet compounds called quercotriterpenosides (QTT) were identified in oak wood used for wine-ageing. The aim of the present study is to discover structural analogs of such natural sweeteners in oak wood. For this purpose, an analytical approach was developed as an alternative to chemical synthesis. Orbitrap mass spectrometry proved to be a crucial technique both to demonstrate the presence of QTT analogs in oak wood by targeted screening and to guide the purification pathway of these molecules using complementary chromatographic tools. Four compounds were isolated and identified for the first time: two isomers, one glucosyl derivative and one galloyl derivative of QTT. Their tasting showed that only the two new isomers were sweet, thus demonstrating both the pertinence of the strategy and the influence of functional groups on gustatory properties. Finally, this paper presents some developments involving multistage Fourier transform mass spectrometry (FTMS) to provide solid structural information on these functional groups prior to any purification of compounds. Such analytical developments could be particularly useful for research on taste-active or bio-active products.
- Subjects :
- Oak wood
Liquid chromatography
Wine
Orbitrap
Mass spectrometry
Biochemistry
High resolution mass spectrometry
Fourier transform ion cyclotron resonance
Mass Spectrometry
Analytical Chemistry
law.invention
chemistry.chemical_compound
Quercus
Isomerism
Computational chemistry
law
[SDV.IDA]Life Sciences [q-bio]/Food engineering
Drug Discovery
Environmental Chemistry
Organic chemistry
Targeted screening
[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering
Spectroscopy
Chromatography, High Pressure Liquid
Biological Products
Fourier Analysis
Sweetness
Wood
Triterpenes
chemistry
Sweetening Agents
Derivative (chemistry)
Subjects
Details
- Language :
- English
- ISSN :
- 00032670
- Database :
- OpenAIRE
- Journal :
- Analytica Chimica Acta, Analytica Chimica Acta, Elsevier Masson, 2015, 853, pp.425-434. ⟨10.1016/j.aca.2014.10.039⟩
- Accession number :
- edsair.doi.dedup.....ce8cb2f8a99e4312e8acbe77883b7206