A Single Dose Monoclonal Antibody Immunoprophylaxis Strategy to Prevent Respiratory Syncytial Virus Disease in All Infants: Results of the First in Infant Study with medi8897

Authors :: Joseph B. Domachowske
Kathryn M Jensen
Filip Dubovsky
Therese Takas
Anis Khan
M. Pamela Griffin
Tonya Villafana
Source :: Pediatrics. 141:256-256
Publication Year :: 2018
Publisher :: American Academy of Pediatrics (AAP), 2018.
Abstract: Purpose: RSV is the most common cause of lower respiratory tract infection (LRTI) among infants. A significant unmet need exists for RSV prevention in healthy infants. Our goal is to develop a monoclonal antibody with an extended half-life (t½) to protect infants through an entire RSV season with a single intramuscular (IM) dose. This study was conducted …

Subjects :: business.industry
medicine.drug_class
Lower respiratory tract infection
Immunology
Pediatrics, Perinatology and Child Health
Medicine
respiratory system
Virus diseases
Respiratory system
business
Monoclonal antibody
medicine.disease
Unmet needs

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