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Peptide-Modified Gemini Surfactants as Delivery System Building Blocks with Dual Functionalities for Glaucoma Treatment: Gene Carriers and Amyloid-Beta (Aβ) Self-Aggregation Inhibitors

Authors :
Lokesh Narsineni
Praveen P. N. Rao
Amy Trinh Pham
Marianna Foldvari
Source :
Molecular pharmaceutics. 19(8)
Publication Year :
2022

Abstract

Retinal ganglion cell (RGC) neurodegeneration in glaucoma has potential links with amyloid-β (Aβ) deposition. Targeting the Aβ pathway was shown to reduce RGC apoptosis and protect RGCs from degeneration. We report exploratory studies on the amyloid Aβ

Details

ISSN :
15438392
Volume :
19
Issue :
8
Database :
OpenAIRE
Journal :
Molecular pharmaceutics
Accession number :
edsair.doi.dedup.....ce1bc462928806014307da5c5036ea30