Back to Search
Start Over
Direct synthesis of chrysosplenol D
- Source :
- Journal of natural products. 71(11)
- Publication Year :
- 2008
-
Abstract
- An aldol condensation and an Algar-Flynn-Oyamada oxidative cyclization were key steps in the direct synthesis of chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
- Subjects :
- Pharmacology
chemistry.chemical_classification
Oxidative cyclization
Molecular Structure
Stereochemistry
Flavone derivatives
Organic Chemistry
Flavonoid
food and beverages
Pharmaceutical Science
Diaphragm pump
Flavones
Chemical synthesis
Analytical Chemistry
Complementary and alternative medicine
chemistry
Artemisia
Cyclization
Drug Discovery
Molecular Medicine
Aldol condensation
Efflux
Oxidation-Reduction
Chrysosplenol D
Subjects
Details
- ISSN :
- 15206025
- Volume :
- 71
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- Journal of natural products
- Accession number :
- edsair.doi.dedup.....cdf629ca015d72d64d214ed63ce3401a