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Association between high-sensitivity cardiac troponin I measured at emergency department and complications of emergency coronary artery bypass grafting
- Source :
- Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019), Scientific Reports
- Publication Year :
- 2019
- Publisher :
- Nature Publishing Group, 2019.
-
Abstract
- High-sensitivity cardiac troponin I (hs-cTnI) is a widely used biomarker to identify ischemic chest pain in the Emergency Department (ED), but the clinical impact on emergency coronary artery bypass grafting (eCABG) remains undetermined. We aimed to evaluate the clinical impact of hs-cTnI measured at the ED by comparing outcomes of eCABG in patients with non–ST-segment–elevation acute coronary syndrome (NSTE-ACS) which comprises unstable angina (UA) and non–ST-segment–elevation myocardial infarction (NSTEMI). From January 2012 to March 2016, 242 patients undergoing eCABG were grouped according to serum hs-cTnI level in the ED. The primary endpoint was major cardiovascular cerebral event (MACCE) defined as a composite of all-cause death, myocardial infarction, repeat revascularization, and stroke. The incidence of each MACCE composite, in addition to postoperative complications such as acute kidney injury, reoperation, atrial fibrillation, and hospital stay duration were also compared. Patients were divided into two groups: UA [p-value = 0.032). In-hospital stay was also longer in the NSTEMI group (9.0 days vs. 15.4 days, p-value = 0.008). ECABG for UA and NSTEMI patients showed comparable outcomes, but hs-cTnI elevation at the ED may be associated with immediate postoperative complications.
- Subjects :
- Male
Emergency Medical Services
Acute coronary syndrome
medicine.medical_specialty
Myocardial Infarction
lcsh:Medicine
Kaplan-Meier Estimate
030204 cardiovascular system & hematology
Predictive markers
Article
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Internal medicine
Odds Ratio
medicine
Humans
030212 general & internal medicine
Myocardial infarction
Acute Coronary Syndrome
Coronary Artery Bypass
lcsh:Science
Stroke
Multidisciplinary
business.industry
Unstable angina
Incidence
Troponin I
lcsh:R
Acute kidney injury
Atrial fibrillation
Emergency department
Prognosis
medicine.disease
ROC Curve
Cardiology
Female
lcsh:Q
Ischemic chest pain
Emergency Service, Hospital
business
Interventional cardiology
Biomarkers
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 9
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....cdda7c6da130197b4f031ce0b2afba21