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The concurrency of several biophysical traits links immunoglobulin light chains with toxicity in AL amyloidosis
- Source :
- Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 26(sup1)
- Publication Year :
- 2019
-
Abstract
- Light chain amyloidosis (LC-AL) is the most common systemic AL. It is caused by the overproduction and the aggregation of toxic and monoclonal immunoglobulin LCs in target organs. Among all the org...
- Subjects :
- integumentary system
Chemistry
Protein Conformation
Amyloidosis
Monoclonal immunoglobulin
Plaque, Amyloid
medicine.disease
Immunoglobulin light chain
Biophysical Phenomena
Protein Aggregates
Biochemistry
Toxicity
Internal Medicine
medicine
AL amyloidosis
Humans
Immunoglobulin Light Chains
Immunoglobulin Light-chain Amyloidosis
Overproduction
Target organ
Subjects
Details
- ISSN :
- 17442818
- Volume :
- 26
- Issue :
- sup1
- Database :
- OpenAIRE
- Journal :
- Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
- Accession number :
- edsair.doi.dedup.....cdb9cb4d20719f757bd6a7535fc1ee9a