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Surveillance Results of Patients with Stage I Nonseminomatous Germ Cell Testicular Cancer
- Source :
- Onkologie. 34:173-176
- Publication Year :
- 2011
- Publisher :
- S. Karger AG, 2011.
-
Abstract
- The aim of this study was to evaluate the efficacy of active surveillance after radical orchiectomy in patients with clinical stage I nonseminoma.Between 2002 and 2009, the charts of 80 patients who were offered active surveillance were studied retrospectively. Patients underwent clinical, radiologic, and biochemical examinations according to NCCN follow-up guidelines in nonseminoma.70 of 80 patients who accepted this strategy were analyzed. 12 of the 70 patients (17%) had relapses with a median follow-up of 18.5 months (6-76). Relapses were found in retroperitoneal lymph nodes in 3 patients. 5 patients had marker relapse, and 4 patients developed both marker relapse and retroperitoneal lymph node metastases. 10 of the 12 patients (83%) had relapsed within 1 year. There were no statistically significant differences in lymphovascular invasion and germ cell components between relapsed and non-relapsed patients. 11 of the 12 patients were treated with cisplatinbased combination chemotherapy, and 1 patient underwent retroperitoneal lymph node dissection. Only 2 patients underwent primary retroperitoneal lymph node dissection for rest nodules.Surveillance could be a reliable strategy in compliant stage I nonseminoma patients. Recurrences can be detected early and treated successfully.
- Subjects :
- Adult
Male
Oncology
Cancer Research
medicine.medical_specialty
Adolescent
Turkey
Young Adult
Testicular Neoplasms
Internal medicine
Prevalence
medicine
Humans
In patient
Stage (cooking)
Young adult
Testicular cancer
Aged
Neoplasm Staging
business.industry
Hematology
General Medicine
Middle Aged
Neoplasms, Germ Cell and Embryonal
medicine.disease
medicine.anatomical_structure
Radical orchiectomy
Population Surveillance
Neoplasm staging
Germ cell tumors
Neoplasm Recurrence, Local
business
Germ cell
Subjects
Details
- ISSN :
- 14230240 and 0378584X
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Onkologie
- Accession number :
- edsair.doi.dedup.....cd4fc7c22c903560b0a3f453c33309c8