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Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis
- Source :
- Current medical science. 40(3)
- Publication Year :
- 2019
-
Abstract
- Cerebellar degeneration-related antigen 1 (CDR1) was described to be expressed in the nervous system and in different types of cancer tissues. In the present study, we demonstrate that CDR1 is in addition ubiquitously expressed in human epidermis, dermis and isolated skin cells. Both CDR1 mRNA and protein were detected in human skin-derived mast cells, melanocytes, fibroblasts and keratinocytes, suggesting that CDR1 does not have a neuron-specific function.
- Subjects :
- Nervous system
Adult
Keratinocytes
Male
Nerve Tissue Proteins
Biology
Biochemistry
Autoantigens
Young Adult
Antigen
Dermis
Genetics
medicine
Cerebellar Degeneration
Humans
RNA, Messenger
Cells, Cultured
Aged
Skin
Messenger RNA
Fibroblasts
Middle Aged
Mast cell
Cell biology
medicine.anatomical_structure
Melanocytes
Female
Epidermis
Keratinocyte
Subjects
Details
- ISSN :
- 2523899X
- Volume :
- 40
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Current medical science
- Accession number :
- edsair.doi.dedup.....cd4a5be362622146594496a3ce0722fb