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Correlations Between Hector Battifora Mesothelial-1 (HBME-1) Expression and Clinical Pathological Characteristics and Prognosis of Osteosarcoma Patients
- Source :
- Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
- Publication Year :
- 2017
- Publisher :
- International Scientific Information, Inc., 2017.
-
Abstract
- BACKGROUND The aim of this study was to investigate the correlation between Hector Battifora mesothelial-1 (HBME-1) expression and the clinical pathological characteristics and prognosis of osteosarcoma (OS). MATERIAL AND METHODS HBME-1 expression was assessed using immunohistochemistry in OS tissues (n=152), osteochondroma tissues (n=91), and normal bone tissues (n=74). We carried out a follow-up lasting 8-60 months to investigate HBME-1 expression and its correlations with the clinical pathological characteristics and prognosis of OS. RESULTS HBME-1 was highly expressed in OS tissues compared with osteochondroma tissues and normal bone tissues, and was highly expressed in osteochondroma tissues compared with normal bone tissues (all P
- Subjects :
- Adult
Male
0301 basic medicine
Osteochondroma
Pathology
medicine.medical_specialty
Epithelial-Mesenchymal Transition
Adolescent
Bone Neoplasms
Metastasis
03 medical and health sciences
0302 clinical medicine
Clinical Research
Recurrence
Risk Factors
Biomarkers, Tumor
medicine
Humans
Risk factor
Child
Survival rate
Pathological
Neoplasm Staging
Osteosarcoma
Receiver operating characteristic
business.industry
General Medicine
Middle Aged
Prognosis
medicine.disease
Immunohistochemistry
030104 developmental biology
ROC Curve
030220 oncology & carcinogenesis
Female
business
Subjects
Details
- ISSN :
- 16433750
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Medical Science Monitor
- Accession number :
- edsair.doi.dedup.....cd30518129b9d0c86e1486f634ceda89