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Practical use of MESNA in atelectatic ears and adhesive otitis media
- Source :
- ORL; journal for oto-rhino-laryngology and its related specialties. 68(4)
- Publication Year :
- 2004
-
Abstract
- Objective: MESNA is a synthetic sulfur compound that produces mucolysis by disrupting disulfide bonds. This study aimed to address indications and technique of MESNA application in otologic surgery, especially in retraction pockets and adhesive otitis media. Methods: MESNA application was performed in 42 ears of 39 patients. The diagnoses were retraction pockets fixed to incudostapedial joint, stapes or promontorium, and adhesive otitis media in 24 and 17 ears, respectively. Calculations were performed according to 24 ears of 23 patients with follow-up data. Results: One or more of the following surgical interventions were performed: MESNA application alone and ventilation tube insertion, reinforcement or mastoidectomy in addition to MESNA application. Sensorineural hearing loss was not encountered after MESNA application. The operation was successful in 79.2%. Overall revision surgery was needed in 20.8% of the ears. In 71.4% of the ears treated with MESNA alone, revision surgery was needed. Conclusion: In the light of our experience, we advocate the use of MESNA in atelectatic ears, because it makes the operation easy and safe by allowing elevation of the tympanic membrane by its mechanical and chemical actions.
- Subjects :
- Adult
medicine.medical_specialty
Tympanic Membrane
Adolescent
Otologic surgery
medicine.medical_treatment
Mastoidectomy
Protective Agents
Ventilation tube
otorhinolaryngologic diseases
medicine
Humans
Adhesive otitis media
Child
Ear Diseases
Mesna
Stapes
Aged
Incudostapedial joint
business.industry
Middle Aged
medicine.disease
Surgery
Otitis Media
medicine.anatomical_structure
Treatment Outcome
Otorhinolaryngology
Sensorineural hearing loss
business
medicine.drug
Subjects
Details
- ISSN :
- 03011569
- Volume :
- 68
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- ORL; journal for oto-rhino-laryngology and its related specialties
- Accession number :
- edsair.doi.dedup.....ccf87c037503d46be0176b6f9bbf0ad2