Back to Search Start Over

Brief Note Low diversity of the major histocompatibility complex class II DRA gene in domestic goats (Capra hircus) in Southern China

Authors :
L.P. Chen
G.X. E
Y.J. Zhao
R.S. Na
Z.Q. Zhao
J.H. Zhang
Y.H. Ma
Y.W. Sun
T. Zhong
H.P. Zhang
Y.F. Huang
Source :
Genetics and Molecular Research. 14:6925-6928
Publication Year :
2015
Publisher :
Genetics and Molecular Research, 2015.

Abstract

DRA encodes the alpha chain of the DR heterodimer, is closely linked to DRB and is considered almost monomorphic in major histocompatibility complex region. In this study, we identified the exon 2 of DRA to evaluate the immunogenetic diversity of Chinese south indigenous goat. Two single nucleotide polymorphisms in an untranslated region and one synonymous substitution in coding region were identified. These data suggest that high immunodiversity in native Chinese population.

Details

ISSN :
16765680
Volume :
14
Database :
OpenAIRE
Journal :
Genetics and Molecular Research
Accession number :
edsair.doi.dedup.....cc9fbea14eece2e35b8386d6b224224c