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FeCl3-catalyzed nucleophilic substitution of propargylic acetates with enoxysilanes
- Source :
- The Journal of organic chemistry. 72(25)
- Publication Year :
- 2007
-
Abstract
- An efficient FeCl3-catalyzed substitution reaction of propargylic acetates with enoxysilanes under mild conditions to afford corresponding gamma-alkynyl ketones has been developed. The substitution reaction is followed by a TsOH-catalyzed cyclization without purification of the gamma-alkynyl ketone intermediates, offering a straightforward synthetic route to tri- or tetrasubstituted furans.
Details
- ISSN :
- 00223263
- Volume :
- 72
- Issue :
- 25
- Database :
- OpenAIRE
- Journal :
- The Journal of organic chemistry
- Accession number :
- edsair.doi.dedup.....cc17685eda05131e2b763f6bba81dbf8