Back to Search
Start Over
Five-year follow-up of a bipolar steroid-eluting ventricular pacing lead
- Source :
- Pacing and clinical electrophysiology : PACE. 22(8)
- Publication Year :
- 1999
-
Abstract
- Steroid-eluting pacing leads are known to attenuate the threshold peaking early after implantation. Long-term performance, however, is not yet settled. The lead design tested in this prospective study combines a 5.8-mm2 tip of microporous platinum-iridium with elution of 1.0 mg of dexamethasone sodium phosphate and tines for passive fixation (model 5024, Medtronic Inc.). In 50 patients (mean age 69 +/- 10 years), the electrode was implanted in the right ventricular apex. Follow-up was performed on days 0, 2, 5, 10, 28, 90, 180 and every 6 months thereafter for 5-years postimplant. At each visit, pacing thresholds were determined as pulse duration (ms) at 1.0 V and as the minimum charge (microC) delivered for capture. Lead impedance (omega) was telemetered at 2.5 V-0.50 ms, and sensing thresholds (mV) were measured in triplicate using the automatic sensing threshold algorithm of the pacemaker implanted (model 294-03, Intermedics Inc.). On the day of implantation, mean values were 0.10 +/- 0.03 ms, 0.12 +/- 0.03 microC, 758 +/- 131 omega, and 13.1 +/- 1.8 mV, respectively. Beyond 1-year postimplant, pacing thresholds did not vary significantly. Sensing thresholds and lead impedance values were stable during long-term follow-up. Five years after implantation, mean values were 0.23 +/- 0.11 ms, 0.24 +/- 0.07 microC, 670 +/- 139 omega, and 11.6 +/- 3.1 mV for pulse width and charge threshold, lead impedance, and sensing threshold, respectively, and all leads captured at 1.0 V with the longest pulse duration available (1.50 ms). It is concluded that the bipolar steroid-eluting tined ventricular lead showed stable stimulation thresholds, lead impedance values, and sensing thresholds for 5 years after implantation.
- Subjects :
- Tachycardia
Adult
medicine.medical_specialty
Pacemaker, Artificial
Ventricular lead
Lead impedance
Dexamethasone
Coated Materials, Biocompatible
Internal medicine
medicine
Humans
Prospective Studies
Lead (electronics)
Glucocorticoids
Aged
Aged, 80 and over
business.industry
Five year follow up
Pulse duration
Mean age
General Medicine
Ventricular pacing
Middle Aged
Surgery
Electrodes, Implanted
Cardiology
Tachycardia, Ventricular
medicine.symptom
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 01478389
- Volume :
- 22
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Pacing and clinical electrophysiology : PACE
- Accession number :
- edsair.doi.dedup.....cbfb6de08b9446eab0dc5adea05e0a33