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Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3

Authors :
Charlotte Hind
Melanie Clifford
Charlotte Woolley
Jane Harmer
Leah M. C. McGee
Izaak Tyson-Hirst
Henry J. Tait
Daniel P. Brooke
Stephanie J. Dancer
Iain S. Hunter
Colin J. Suckling
Rebecca Beveridge
John A. Parkinson
J. Mark Sutton
Fraser J. Scott
Source :
ACS Infectious Diseases. 8:2552-2563
Publication Year :
2022
Publisher :
American Chemical Society (ACS), 2022.

Abstract

MGB-BP-3 is a potential first-in-class antibiotic, a Strathclyde Minor Groove Binder (S-MGB), that has successfully completed Phase IIa clinical trials for the treatment of

Subjects

Subjects :
Infectious Diseases

Details

ISSN :
23738227
Volume :
8
Database :
OpenAIRE
Journal :
ACS Infectious Diseases
Accession number :
edsair.doi.dedup.....cbd40ee75d50fe78bef77a7f42c5f6f2
Full Text :
https://doi.org/10.1021/acsinfecdis.2c00445