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Current trends in safety testing and toxicological research
- Source :
- Naturwissenschaften. 69:255-259
- Publication Year :
- 1982
- Publisher :
- Springer Science and Business Media LLC, 1982.
-
Abstract
- The paper reviews current concepts of toxicological evaluation of new drugs and other chemicals. Instead of completing a predetermined check-list toxicologists now consider the potential adverse effects of the substances under actual conditions of use. They then design experimental models which have a high probability to predict the toxic effects. Moreover, the enhanced susceptibilities of special risk populations is more and more taken into consideration.
- Subjects :
- High probability
Clinical Trials as Topic
Experimental model
business.industry
Drug Evaluation, Preclinical
General Medicine
Toxicology
United States
Risk analysis (engineering)
Animals
Drug Evaluation
Humans
Medicine
Safety
Current (fluid)
Adverse effect
business
Safety testing
Ecology, Evolution, Behavior and Systematics
Subjects
Details
- ISSN :
- 14321904 and 00281042
- Volume :
- 69
- Database :
- OpenAIRE
- Journal :
- Naturwissenschaften
- Accession number :
- edsair.doi.dedup.....cbc97269b1f021f7cbcd49044f1e8dac