Back to Search
Start Over
Effects of elevated core temperature and normoxic 30% nitrous oxide on human ventilation during short duration, high intensity exercise
- Source :
- Respiratory Physiology & Neurobiology. 206:19-24
- Publication Year :
- 2015
- Publisher :
- Elsevier BV, 2015.
-
Abstract
- It was hypothesized that normoxic 30% nitrous oxide (N2O) would suppress and hyperthermia would increase exercise ventilation during short duration, high intensity exercise. Thirteen males (24.2±0.8y; mean±SE), of normal physique (BMI, 23.8±1.0kgm(-2)), performed 4 separate 30s Wingate tests on a cycle ergometer. Exercise ventilation and its components, as well as mean skin and esophageal temperature (TES), were assessed in 2 way experimental design with factors of Thermal State (Normothermia or Hyperthermia) and Gas Type (Air or 30% Normomoxic N2O). In the 2 hyperthermic tests TES was elevated to ∼38.5°C in a 40°C bath. The main results indicated a significant interaction (F=7.14, P=0.02) between Gas Type and Thermal state for the exercise-induced increase in ventilation (ΔV˙E). During both the normothermia and hyperthermia conditions with AIR breathing, the exercise ΔV˙E was ∼80Lmin(-1) and it was significantly decreased to 73.1±24.1Lmin(-1) in the normothermia condition with N2O breathing relative to that of 92.0±25.0Lmin(-1) in the hyperthermia condition with N2O breathing. In conclusion, normoxic N2O breathing suppressed high intensity exercise ventilation during normothermia relative to that during hyperthermia on account of decreases in the tidal volume and this led CO2 retention.
- Subjects :
- Adult
Male
Pulmonary and Respiratory Medicine
Hyperthermia
Time Factors
Ergometry
Fever
Physiology
Nitrous Oxide
Young Adult
chemistry.chemical_compound
Oxygen Consumption
Respiration
Tidal Volume
medicine
Humans
Exercise
Short duration
Tidal volume
Chemistry
General Neuroscience
High intensity
Nitrous oxide
equipment and supplies
medicine.disease
Anesthesia
Breathing
Inert Gas Narcosis
Body Temperature Regulation
Subjects
Details
- ISSN :
- 15699048
- Volume :
- 206
- Database :
- OpenAIRE
- Journal :
- Respiratory Physiology & Neurobiology
- Accession number :
- edsair.doi.dedup.....cbb0d6421db15a80197b32b5a40f8c50