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Plasma concentrations of beta-carotene, vitamin A and vitamin E after beta-carotene and vitamin E intake
- Source :
- Biomedical chromatography : BMC. 7(3)
- Publication Year :
- 1993
-
Abstract
- We have studied the metabolism (absorption) of beta-carotene and vitamin E by assigning eleven volunteers to receive daily two capsules of OENOBIOL, each containing 15 mg of beta-carotene and 15 mg of vitamin E, over 60 days. The beta-carotene, vitamin E and vitamin A plasma levels were then determined using new methods developed in our laboratory. After two months, the actively treated group's median beta-carotene and vitamin E levels were significantly higher than those of a control group. However, no significant change between treated and control groups in the mean of vitamin A (retinol) plasma levels were observed. Treatment with beta-carotene, a vitamin A precursor, does not significantly modify the vitamin A levels. This conclusion had already been observed and it is assumed that a plasma level of beta-carotene equal or higher than 0.3 mg/L reflects a nutritional intake of provitamins sufficient to support homeostasis of retinol (Brubacher et al., 1982).
- Subjects :
- Vitamin
Adult
Male
medicine.medical_specialty
medicine.medical_treatment
Clinical Biochemistry
Biochemistry
Analytical Chemistry
Absorption
chemistry.chemical_compound
BETA CAROTENE/VITAMIN A
beta-Carotene
Internal medicine
Drug Discovery
medicine
Homeostasis
Humans
Vitamin E
Vitamin A
Molecular Biology
Chromatography, High Pressure Liquid
Pharmacology
Chromatography
Provitamin
Retinol
General Medicine
Metabolism
beta Carotene
Carotenoids
Endocrinology
chemistry
Female
Subjects
Details
- ISSN :
- 02693879
- Volume :
- 7
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Biomedical chromatography : BMC
- Accession number :
- edsair.doi.dedup.....cb26fd0f8885d5cc0bb4f618a2e36799